Exploring the Potential of Deep Learning in Parkinson's Disease Drug Discovery
Complex and complex neurological illnesses like Parkinson's Disease (PD) are difficult to investigate. This publication introduces “Neural Pathway Profiling for Parkinson's Disease Drug Discovery.” It leverages cutting-edge deep learning. GCNs explain molecular interactions, LSTMs examine temporal sequences, and VAEs learn by forming new patterns. Our research uses genes, proteins, and clinical data to explain how Parkinson's disease's various components interact in complex ways. LSTMs illustrate how clinical data is connected to time, GCNs reveal how molecules interact in biological networks, and VAEs discover hidden chemical structures for generative learning. The blended design reveals key brain connections and Parkinson's disease therapeutic targets.
Authors
- C. Raja (ORCID: https://orcid.org/0000-0001-7351-3403)
- Ravula Arun Kumar
- Munish Kumar (ORCID: https://orcid.org/0000-0003-0115-1620)
- Tejashree Tejpal Moharekar (ORCID: https://orcid.org/0000-0002-0860-4373)
- A. Nirisha
- M. Ponnrajakumari
Institutions
- Vel Tech Rangarajan Dr. Sagunthala R&D Institute of Science and Technology (IN)
- Shivaji University (IN)
- Koneru Lakshmaiah Education Foundation (IN)
Publication Details
- Published
- 2024-09-27
- DOI
- https://doi.org/10.1109/acroset62108.2024.10743510
- Citations
- 1
- Primary Topic
- Computational Drug Discovery Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.36