Perinatal health in a cohort of children conceived after assisted reproduction in the UK: a population-based record-linkage study
Children conceived via assisted reproduction showed modest increases in the risk of hospitalisations for severe perinatal events when compared with population controls, although these findings were attenuated in the sibling analyses. The imprecision of within-sibling analyses highlights the need for larger studies to explore potential causal effects.
Authors
- Daniel R. Brison (ORCID: https://orcid.org/0000-0002-4307-1293)
- Mitana Purkayastha (ORCID: https://orcid.org/0000-0002-1870-8838)
- Scott McGill Nelson (ORCID: https://orcid.org/0000-0002-9099-3047)
- Debbie A. Lawlor (ORCID: https://orcid.org/0000-0002-6793-2262)
- Alastair Sutcliffe (ORCID: https://orcid.org/0000-0001-8542-6155)
- Stephen A. Roberts
Institutions
- Manchester Academic Health Science Centre (GB)
- University of Manchester (GB)
- University of Bristol (GB)
- Department of Science and Technology (IN)
- NIHR Bristol Biomedical Research Centre (GB)
- MRC Epidemiology Unit (GB)
- University College London (GB)
- University of Glasgow (GB)
Publication Details
- Journal
- BMJ Open
- Published
- 2024-11-01
- DOI
- https://doi.org/10.1136/bmjopen-2024-091910
- Citations
- 1
- Primary Topic
- Assisted Reproductive Technology and Twin Pregnancy
- Type
- article
- Field-Weighted Citation Impact
- 1.11
Funders
- National Institute for Health and Care Research
- University of Bristol
- Medical Research Council
- European Research Council