Integrative Lipid Pseudotargeted Metabolomics and Amino Acids Targeted Metabolomics Unravel the Therapeutic Mechanism of Rhizoma Paridis Saponins on Experimental Colitis of Damp-Heat Type
These results showed that RPTS (50 mg/kg) and PN (20 mg/kg) effectively alleviated rats' colitis of damp-heat type, affected cytokines, and altered lipid metabolism without significant modulation on amino acid metabolism.
Authors
- Changyin Li (ORCID: https://orcid.org/0000-0001-6232-966X)
- Kexin Liu (ORCID: https://orcid.org/0000-0001-6116-1922)
- Xingxing Wu (ORCID: https://orcid.org/0000-0002-6339-4348)
- Genglin Mu (ORCID: https://orcid.org/0000-0002-0903-5475)
- Qi Wu (ORCID: https://orcid.org/0000-0001-8717-4174)
- Lingchang Meng (ORCID: https://orcid.org/0000-0002-1862-5864)
- Mao Wang
- Guoliang Dai (ORCID: https://orcid.org/0000-0001-8319-9374)
- R を胸壁欠如部分に固定後
- Jing Wu (ORCID: https://orcid.org/0000-0001-5733-0500)
- Xiaoyu Ruan
- Zhiting Sun (ORCID: https://orcid.org/0000-0002-1649-2084)
Institutions
- Nanjing University of Chinese Medicine (CN)
- Henan University of Traditional Chinese Medicine (CN)
- People's Liberation Army 401 Hospital (CN)
- Zhengzhou City Hospital (CN)
- Nanjing Drum Tower Hospital (CN)
- Zhengzhou People's Hospital (CN)
Publication Details
- Journal
- Drug Design Development and Therapy
- Published
- 2024-11-01
- DOI
- https://doi.org/10.2147/dddt.s476494
- Citations
- 3
- Primary Topic
- Pharmacological Effects of Natural Compounds
- Type
- article
- Field-Weighted Citation Impact
- 1.40
Funders
- National Natural Science Foundation of China
- Nanjing Drum Tower Hospital