The Use of Zolpidem in Catatonia: A Case Report

Catatonia is a complex neuropsychiatric syndrome characterised by abnormal psychomotor disturbance, which poses a diagnostic and treatment challenge to clinicians. It is a life-threatening condition in its severe form, termed malignant and characterised by hyperthermia and autonomic disturbances. Early recognition and treatment are important in its management. A screening instrument, such as the Bush-Francis Catatonia Rating Scale (BFCRS), can help the clinician make a prompt diagnosis. Only a few published cases describe zolpidem being used to treat this condition, with lorazepam and electroconvulsive therapy (ECT) more commonly utilised as part of established treatment protocols. We discuss a case of a 70-year-old female with treatment-resistant depression and catatonic features who was successfully managed with zolpidem. This report highlights the role and efficacy of zolpidem in the clinical management of catatonia.