Brain neurovascular coupling in amyotrophic lateral sclerosis: Correlations with disease progression and cognitive impairment
The reduction of brain NVC in the DMN may reflect largely distributed abnormalities of the neurovascular unit. NVC alterations in the DMN could play a role in anticipating a faster clinical progression in ALS patients, aiding patient selection and monitoring during clinical trials.
Authors
- Federica Di Nardo (ORCID: https://orcid.org/0000-0003-0812-9290)
- Ilaria Orologio
- Antonietta Canna (ORCID: https://orcid.org/0000-0003-1058-9456)
- Francesca Trojsi (ORCID: https://orcid.org/0000-0002-3790-8018)
- Fabrizio Canale
- Minoo Sharbafshaaer (ORCID: https://orcid.org/0000-0001-9887-5304)
- Maria Agnese Pirozzi (ORCID: https://orcid.org/0000-0002-4632-3513)
- Fabrizio Esposito (ORCID: https://orcid.org/0000-0002-5099-9786)
- Mattia Siciliano (ORCID: https://orcid.org/0000-0001-5246-2109)
- Carla Passaniti (ORCID: https://orcid.org/0000-0001-5367-8139)
- Antonio Russo (ORCID: https://orcid.org/0000-0002-0601-0475)
- Mario Cirillo (ORCID: https://orcid.org/0000-0001-5350-7700)
- Alessandro Tessitore (ORCID: https://orcid.org/0000-0002-2913-6548)
- Marcello Silvestro (ORCID: https://orcid.org/0009-0002-3288-1685)
Institutions
- Montreal Neurological Institute and Hospital (CA)
- St George's, University of London (GB)
- University of Campania "Luigi Vanvitelli" (IT)
- McGill University (CA)
Publication Details
- Journal
- European Journal of Neurology
- Published
- 2024-11-11
- DOI
- https://doi.org/10.1111/ene.16540
- Citations
- 4
- Primary Topic
- Amyotrophic Lateral Sclerosis Research
- Type
- article
- Field-Weighted Citation Impact
- 1.48