Dynamics of cervical intraepithelial neoplasia according to cytological and morphological data on the example of women’s consultations in Yekaterinburg

Aim. To analyze the dynamics of cervical intraepithelial neoplasia according to cytology and morphology data on the example of women’s consultations in Yekaterinburg.Materials and methods. A descriptive epidemiological study was conducted. The authors analyzed data from reports on the work of the cervical pathology office on the basis of two women’s consultations in Yekaterinburg: the women’s consultation No. 1 of Central City Clinical Hospital No. 6 and the women’s consultation No. 2 of Central City Clinical Hospital No. 6 for the period from the 1st quarter of 2022 to the 2nd quarter of 2023.Results. The number of results on the absence of pathological changes in the cytological examination of the cervix (negative for intraepithelial lesion or malignancy, NILM) increased quarterly in both the city’s women’s consultations during the analyzed time period. Low-grade squamous intraepithelial lesion (LSIL) has the highest proportion in the structure of abnormal cytological results. The observation group in the women’s consultation No. 1 is almost 2 times larger than in the women’s consultation No. 2 (р = 0.0048). Statistically significant differences are observed only in the frequency of ASC-US (р = 0.049). The authors did not reveal statistically significant differences in the findings of histological studies of cervical tissue.Conclusion. After Order No. 521p entered into force in Yekaterinburg, a larger number of patients were covered by cytological screening. The number of normal results increased due to healthy women, but the frequency of abnormal cytology results remains at the same level. This may be due to increased accessibility and improved quality of medical care. In patients who have undergone cervical screening, secondary prevention of cervical cancer can be effectively carried out.