Asymptomatic Cerebrospinal Fluid HIV-1 Escape: Incidence and Consequences

Asymptomatic CSFE was identified in only 4 (2%) PWH, with no cases of continuous CSFE observed. Increased CSF HIV-1 RNA was associated with biomarkers of CNS immune activation and blood-brain barrier impairment, but not with biomarkers of neuronal injury.

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Publication Details

Journal
The Journal of Infectious Diseases
Published
2024-11-08
DOI
https://doi.org/10.1093/infdis/jiae555
Citations
5
Primary Topic
HIV Research and Treatment
Type
article
Field-Weighted Citation Impact
1.47

Funders

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article

Asymptomatic Cerebrospinal Fluid HIV-1 Escape: Incidence and Consequences

Erika Tyrberg, Staffan Nilsson, Erik Sörstedt, Johanna M. Gostner et al.
5 citations
The Journal of Infectious Diseases
HIV Research and Treatment
1.47
article

Asymptomatic Cerebrospinal Fluid HIV-1 Escape: Incidence and Consequences

Erika Tyrberg, Staffan Nilsson, Erik Sörstedt, Johanna M. Gostner, Magnus Gisslén, Gustaf Ulfhammer, Arvid Edén, Lars Hagberg, Åsa Mellgren, Kristina Nystrôm, Henrik Zetterberg, Dietmar Fuchs, Aylin Yilmaz
article en
5 citations

Abstract

Asymptomatic CSFE was identified in only 4 (2%) PWH, with no cases of continuous CSFE observed. Increased CSF HIV-1 RNA was associated with biomarkers of CNS immune activation and blood-brain barrier impairment, but not with biomarkers of neuronal injury.

The Journal of Infectious DiseasesVol. 231(2)
Public Health Agency of Sweden (SE), University of Wisconsin–Madison (US), Innsbruck Medical University (AT), Sahlgrenska University Hospital (SE), UK Dementia Research Institute (GB), University College London (GB), University of Gothenburg (SE)
Vetenskapsrådet
Good health and well-being
Openalex Percentile: Top 17%
HIV Research and Treatment
1.47
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Asymptomatic Cerebrospinal Fluid HIV-1 Escape: Incidence and Consequences — Erika Tyrberg, Staffan Nilsson, et al. · The Journal of Infectious Diseases (2024) | TGRS Research Map | TGRS