The role of CISD1 reduction in macrophages in promoting COPD development through M1 polarization and mitochondrial dysfunction
Smoke-induced reduction of CISD1 in macrophages promotes M1 polarization and mitochondrial dysfunction by activating the autophagy pathway, thereby promoting the occurrence and development of COPD.
Authors
- Jiameng Gao (ORCID: https://orcid.org/0000-0003-4161-938X)
- Zhilong Jiang (ORCID: https://orcid.org/0000-0001-6217-5082)
- Yuning Qian
- Weibin Tian
- Zhihong Chen (ORCID: https://orcid.org/0000-0003-3849-6331)
- Meiyuan Dong
- Yao Shen (ORCID: https://orcid.org/0000-0001-9382-3687)
- Junyi Xia (ORCID: https://orcid.org/0009-0004-2431-9160)
Institutions
- Second Military Medical University (CN)
- Fudan University (CN)
- Zhongshan Hospital (CN)
- Pudong Medical Center (CN)
- Shanghai Pudong New Area Gongli Hospital (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2024-11-13
- DOI
- https://doi.org/10.1186/s40001-024-02146-2
- Citations
- 4
- Primary Topic
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Type
- article
- Field-Weighted Citation Impact
- 1.68