Clinical evaluation of PRG Barrier coat versus fluoride varnish on the color improvement of white spot lesions in permanent teeth of children: a randomized controlled trial

Background White spot lesions (WSLs) are common in dentistry, remineralizing agents like fluoride and Surface pre-reacted glass filler (S-PRG filler)are used to prevent, treat, and improve their color. This study aims to evaluate the clinical effectiveness of S-PRG versus fluoride varnish in remineralizing and color-improving the white spot lesions in children's permanent anterior teeth and patient response to the treatment.Methods Patients were randomly selected and divided into 2 groups; group (A) received Giomer varnish with (S-PRG), group (B) received 5% NaF fluoride varnish . The WSLs were assessed clinically using a spectrophotometer at baseline, after 1, 3, and 6 months. 'Participants' anxiety in response to the treatment was assessed using the facial visual scale. For every test, the mean and standard deviation have been calculated for every group. Results There was no statistically significant difference in the values of ∆E and ∆E00 between base line-1 month, 3month, and 6month groups where (p=0.461) in both groups. Comparing the results of the two groups to each other, There was a statistically significant difference in ∆E and ∆E00 of Baseline to 1-month values of S-PRG where ΔEab (7.72) and ΔE00 (6.61) and Fluoride varnish where ΔEab (11.96) and ΔE00 (8.38) where (p=0.003). No statistically significant difference could be found between S-PRG and Fluoride varnish where (p=0.655) concerning the 'Participants' anxiety.Conclusions Within the study's limitations, PRG Barrier Coat resulted in more improved enamel color than the fluoride varnish one month after application, though not to the required level of esthetics.