Pretreatment with Notoginsenoside R1 enhances the efficacy of neonatal rat mesenchymal stem cell transplantation in model of myocardial infarction through regulating PI3K/Akt/FoxO1 signaling pathways
NGR1 pretreatment enhances the effect of MSC transplantation for treatment of MI through paracrine signaling, and the mechanism underlying this effect may be associated with PI3K/Akt/FoxO1 signaling pathways.
Authors
- Fang-fang Mou
- Zhi-Rong Luo (ORCID: https://orcid.org/0000-0002-8585-6865)
- Hao Cai (ORCID: https://orcid.org/0000-0003-1024-647X)
- Zhinan Zhao
- Pingping Lu
- Dan Hu (ORCID: https://orcid.org/0000-0002-0994-8434)
- Hai-dong Guo (ORCID: https://orcid.org/0000-0003-1641-9562)
- Qiang‐Li Wang
- Han Xiaojing
Institutions
- Shanghai University of Traditional Chinese Medicine (CN)
- Shanghai Traditional Chinese Medicine Hospital (CN)
- Seventh People's Hospital of Shanghai (CN)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2024-11-13
- DOI
- https://doi.org/10.1186/s13287-024-04039-x
- Citations
- 10
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 2.85
Funders
- Shanghai Municipal Health Commission
- National Natural Science Foundation of China
- Program of Shanghai Academic Research Leader