Prolonged venous transit is associated with worse neurological recovery in successfully reperfused large vessel strokes
PVT+ was significantly associated with reduced neurological improvement despite successful reperfusion in AIS-LVO patients, highlighting the critical role of VO impairment in short-term functional outcomes. These findings further validate PVT as a valuable adjunct imaging biomarker derived from CTP for assessing VO profiles in AIS-LVO.
Authors
- Jeremy Josef Heit (ORCID: https://orcid.org/0000-0003-1055-8000)
- Argye E. Hillis (ORCID: https://orcid.org/0000-0002-5192-1171)
- Risheng Xu (ORCID: https://orcid.org/0000-0003-4288-1232)
- Tobias Djamsched Faizy (ORCID: https://orcid.org/0000-0002-1631-2020)
- R. Llinás (ORCID: https://orcid.org/0000-0002-9161-2699)
- Benjamin Pulli (ORCID: https://orcid.org/0000-0002-1795-9897)
- Gaurang Shah (ORCID: https://orcid.org/0000-0002-1370-3173)
- Hanzhang Lu (ORCID: https://orcid.org/0000-0003-3871-1564)
- Gregory W. Albers (ORCID: https://orcid.org/0000-0003-0263-4632)
- Hamza Adel Salim (ORCID: https://orcid.org/0000-0002-5208-8425)
- Dylan Wolman (ORCID: https://orcid.org/0000-0002-5012-1690)
- Rich Leigh
- Dhairya A. Lakhani (ORCID: https://orcid.org/0000-0001-7577-1887)
- Kambiz Nael (ORCID: https://orcid.org/0000-0002-4194-9488)
- Vaibhav Vagal (ORCID: https://orcid.org/0000-0002-8977-2167)
- Adam Andrew Dmytriw (ORCID: https://orcid.org/0000-0003-0131-5699)
- Francis Deng (ORCID: https://orcid.org/0000-0003-3117-5076)
- Max Wintermark (ORCID: https://orcid.org/0000-0002-6726-3951)
- Janet Mei (ORCID: https://orcid.org/0000-0003-4184-8924)
- Aneri Balar (ORCID: https://orcid.org/0000-0002-3592-708X)
- Victor Urrutia (ORCID: https://orcid.org/0000-0002-4995-6949)
- Elisabeth B. Marsh (ORCID: https://orcid.org/0000-0002-2385-5074)
- Vivek Srikar Yedavalli (ORCID: https://orcid.org/0000-0002-2450-4014)
- Adrien Guenego (ORCID: https://orcid.org/0000-0001-7281-1652)
- Licia Luna (ORCID: https://orcid.org/0000-0003-3539-4831)
- Nathan Z. Hyson (ORCID: https://orcid.org/0009-0003-2758-3402)
- Mona Shahriari (ORCID: https://orcid.org/0000-0002-1191-7557)
Institutions
- St. Michael's Hospital (CA)
- The University of Texas MD Anderson Cancer Center (US)
- Harvard University (US)
- Johns Hopkins University (US)
- University of California, San Francisco (US)
- Brown University (US)
- University of Michigan (US)
- Erasmus Hospital (BE)
- Johns Hopkins Bayview Medical Center (US)
- University of California System (US)
- Stony Brook School (US)
- Massachusetts General Hospital (US)
- University Hospital Münster (DE)
- Stanford Medicine (US)
- Stony Brook University (US)
Publication Details
- Journal
- Annals of Clinical and Translational Neurology
- Published
- 2024-11-11
- DOI
- https://doi.org/10.1002/acn3.52243
- Citations
- 24
- Primary Topic
- Acute Ischemic Stroke Management
- Type
- article
- Field-Weighted Citation Impact
- 9.28