HEMODYNAMICS OF THE BRAIN IN NEWBORNS FROM MOTHERS WITH PLACENTAL INSUFFICIENCY

Objective. To determine the state of brain structures and blood flow parameters in the ventricular system in newborns whose mothers suffered from placental insufficiency using neurosonography and Doppler ultrasound. Material and methods. The study involved 96 newborns from mothers with placental insufficiency (the main group) and 30 healthy newborns (the control group). The diagnostic tools included a neurosonographic assessment of the anterior and middle cranial fossae, as well as Doppler ultrasound of the anterior and middle cerebral arteries, vein of Galen blood flow velocity assessment, systolic/diastolic ratio (S/D), resistive index (Ri) and pulsatility index (PI). Results. The comparative analysis of blood flow in the anterior cerebral artery and the vein of Galen did not reveal statistically significant differences between the main and control groups. While examining the middle cerebral artery, despite the absence of statistically significant differences in blood flow velocities compared with the control group, resistive index (Ri), pulsatility index (Pi) and systolic/diastolic ratio (S/D) showed statistically significant differences. This indicates increased vascular resistance in newborns from the main group. Conclusion. It is essential to combine Doppler ultrasound and neurosonography in order to make an objective assessment of the state of the newborns central nervous system from mothers with placental insufficiency. The study revealed impairment of hemodynamics in the middle cerebral arteries pool in newborns from the main group. To assess cerebral hemodynamics, it is preferable to use the Ri, Pi and S/D indices.