Antibiotic Resistance in Acne Treatment: Emerging Challenges and Implications for Dermatology Practice in Developing Countries like Bangladesh

Background: Antibiotic resistance in acne treatment is an escalating global issue, particularly in developing countries like Bangladesh, where misuse of antibiotics is prevalent. Objective: To assess the prevalence of antibiotic-resistant Cutibacterium acnes and its implications for acne treatment efficacy at Aurora Skin and Aesthetics in Dhaka, Bangladesh. Methods: A cross-sectional study was conducted from September 2021 to March 2022 at Aurora Skin and Aesthetics, Dhaka. A total of 100 acne patients were selected, and antibiotic sensitivity tests were performed on C. acnes strains isolated from lesion swabs. The data was analyzed to determine the resistance to commonly prescribed antibiotics like tetracyclines, erythromycin, and clindamycin. Results: Out of 100 patients, 45% were male and 55% were female. Among the isolated C. acnes strains, 60% showed resistance to erythromycin, 40% to clindamycin, and 35% to tetracyclines. A significant percentage (25%) of patients resisted more than one antibiotic. Patients with antibiotic-resistant acne exhibited a 30% longer treatment duration compared to non-resistant cases, with only 50% achieving satisfactory Improvement after 12 weeks of standard antibiotic therapy. Conclusions: The study highlights the growing problem of antibiotic resistance in acne treatment in Bangladesh, emphasizing the need for stricter antibiotic use guidelines and alternative therapies to improve treatment outcomes.