Metformin Attenuates Myocardial Ischemia-Reperfusion Injury through the AMPK-HMGCR-ROS Signaling Axis
MET inhibits the expression of HMGCR by activating AMPK, reduces oxidative damage and apoptosis of cardiomyocytes, and alleviates myocardial ischemia-reperfusion injury.
Authors
- Xinmei Zhang (ORCID: https://orcid.org/0000-0001-7122-6435)
- Tao Zhu (ORCID: https://orcid.org/0000-0001-9327-3590)
- He Zhu
- Dubiao Dubiao
Institutions
- Zhejiang Chinese Medical University (CN)
- Wenzhou Medical University (CN)
Publication Details
- Journal
- Kardiologiia
- Published
- 2024-10-31
- DOI
- https://doi.org/10.18087/cardio.2024.10.n2739
- Citations
- 1
- Primary Topic
- Metabolism, Diabetes, and Cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.23