RADIOFREQUENCY ABLATION AS A MINIMALLY INVASIVE TREATMENT FOR BENIGN THYROID NODULES: A CLINICAL STUDY

Background: While benign thyroid nodules are often asymptomatic, they can cause cosmetic concerns and physical discomfort, leading to the need for treatment. Radiofrequency ablation (RFA) has gained attention as a non-surgical option to reduce nodule size and alleviate symptoms. This study investigates the effectiveness of RFA in treating benign thyroid nodules and its impact on nodule volume and related clinical symptoms. A total of 20 benign thyroid nodules in 15 pat Methods: ients were treated with RFA after obtaining informed consent. Patients were followed for six months' post-treatment. Inclusion criteria consisted of patients with unilateral or bilateral nodules that caused cosmetic or compressive symptoms, confirmed benignity via cytology twice, and those who either declined or were ineligible for surgery. Prior to ablation, cystic nodules were aspirated. RFA was performed using a STARMED RF generator. Nodule volume, symptom relief, and any complications were assessed before and after the procedure. Significant reduct Results: ion in nodule volume was observed, with a mean volume reduction ratio (VRR) of 42.6% at 1 month, 61.5% at 3 months, and 73.1% at 6 months (p < 0.001). Symptom resolution and cosmetic improvement were achieved in all patients, with no adverse effects on thyroid function. No serious complications were reported. Radiofrequency ablation proves to be a safe and effective treatment option for benign thyroi Conclusion: d nodules, offering a minimally invasive alternative to surgery. The procedure demonstrated notable improvements in nodule size and patient symptoms, making it a valuable therapeutic approach. Further studies with extended follow-up will help define its long-term role in thyroid nodule management.