Neuropathological Correlates of White Matter Hyperintensities in Cerebral Amyloid Angiopathy
This study confirmed that vascular amyloid β severity in the cortex is significantly associated with WMH volume in patients with definite CAA. The histopathological substrates of both posterior confluent and WMH multispots were comparable, suggesting overlapping pathophysiological mechanisms, although these exploratory observations require confirmation in larger studies.
Authors
- Susanne J. van Veluw (ORCID: https://orcid.org/0000-0002-7957-8643)
- Valentina Perosa (ORCID: https://orcid.org/0000-0002-3551-5237)
- Maria Clara Zanon Zotin (ORCID: https://orcid.org/0000-0001-6604-0660)
- Juan Eugenio Iglesias (ORCID: https://orcid.org/0000-0001-7569-173X)
- Steven Mark Greenberg (ORCID: https://orcid.org/0000-0003-1792-8887)
- Nazanin Makkinejad (ORCID: https://orcid.org/0000-0001-8153-743X)
- Hilde van den Brink (ORCID: https://orcid.org/0000-0003-3094-0274)
- Corinne A. Auger (ORCID: https://orcid.org/0000-0002-7238-4504)
- Kali A. vom Eigen
Institutions
- Harvard University (US)
- Universidade de São Paulo (BR)
- Massachusetts General Hospital (US)
- MaineGeneral Medical Center (US)
- Athinoula A. Martinos Center for Biomedical Imaging (US)
- University College London (GB)
Publication Details
- Journal
- Journal of the American Heart Association
- Published
- 2024-11-11
- DOI
- https://doi.org/10.1161/jaha.124.035744
- Citations
- 6
- Primary Topic
- Intracerebral and Subarachnoid Hemorrhage Research
- Type
- article
- Field-Weighted Citation Impact
- 2.21