Pomegranate Peel Extract Mitigates Diarrhea-Predominant Irritable Bowel Syndromes via MAPK and NF-κB Pathway Modulation in Rats
The present study is the first to demonstrate that PPE alleviates diarrheal and intestinal damage in IBS-D, potentially by inhibiting MAPK and NF-κB signaling pathways. These findings suggest that PPE may provide a novel therapeutic option for IBS-D.
Authors
- Zhihui Hao (ORCID: https://orcid.org/0000-0001-9516-6270)
- Jianzhong Shen (ORCID: https://orcid.org/0000-0002-8502-8445)
- Sijuan Huang
- Yannan Zhang (ORCID: https://orcid.org/0000-0001-5992-250X)
- Shuai Zhang (ORCID: https://orcid.org/0009-0006-5027-8213)
Institutions
- Ministry of Agriculture and Rural Affairs (CN)
- China Agricultural University (CN)
Publication Details
- Journal
- Nutrients
- Published
- 2024-11-11
- DOI
- https://doi.org/10.3390/nu16223854
- Citations
- 7
- Primary Topic
- Pomegranate: compositions and health benefits
- Type
- article
- Field-Weighted Citation Impact
- 2.17