Knowledge, attitude, and perception of exercises among post-hematopoietic stem cell transplant patients: A cross-sectional study

Exercise rehabilitation is crucial for the recovery after hematopoietic stem cell transplantation (HSCT). This study aimed to investigate knowledge, attitude, and perception (KAP) of exercise among post-HSCT patients. This cross-sectional study was conducted at Zhujiang Hospital, Southern Medical University between January 2020 and December 2022 among post-HSCT patients, using a self-designed questionnaire. A total of 192 patients were included, with the mean age of 37.90 ± 11.96 years; 116 (60.42%) reported to exercise before. The mean KAP scores were 9.22 ± 2.05 (possible range: 0-12), 43.51 ± 5.47 (possible range: 12-60) and 51.79 ± 7.45 (possible range: 15-75), respectively. Patients previously inactive in exercise exhibited significant differences in KAP scores from active patients: attitude total score, positive attitude, perception total score, willingness to exercise, aerobic exercise, breathing training (all P < .001), with a noteworthy distinction in resistance exercise (P = .018). According to structural equation modeling, perception was directly influenced by knowledge (β = 0.87, P < .001), attitude (β = 0.26, P = .007), and exercise habits (β = 3.36, P = .001), as well as indirectly by education (β = 0.44, P = .010) and knowledge (β = 0.18, P = .029). Post-HSCT patients had adequate knowledge, moderate attitude and perception of exercises, even 1 year after HSCT. Patients inactive in exercises exhibited significant differences in knowledge and exercise perception from active patients. Healthcare professionals should tailor education, target attitude, and personalize exercise plans to facilitate effective recovery post-HSCT.