Anhedonia is associated with a specific depression profile and poor antidepressant response

Our findings support the role of anhedonia as a modulating feature of MDD, being associated with a more severe depression profile. Moreover, anhedonic features are independent predictors of poor treatment response.

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Publication Details

Journal
The International Journal of Neuropsychopharmacology
Published
2024-11-10
DOI
https://doi.org/10.1093/ijnp/pyae055
Citations
24
Primary Topic
Treatment of Major Depression
Type
article
Field-Weighted Citation Impact
10.75

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article

Anhedonia is associated with a specific depression profile and poor antidepressant response

Stuart Montgomery, Joseph Zohar, Raffaele Ferri, Basilio Pecorino et al.
24 citations
The International Journal of Neuropsychopharmacology
Treatment of Major Depression
10.75
article

Anhedonia is associated with a specific depression profile and poor antidepressant response

Stuart Montgomery, Joseph Zohar, Raffaele Ferri, Basilio Pecorino, Panagiotis P. Ferentinos, Julien Mendlewicz, Raffaella Zanardi, Giuseppe Fanelli, Bernhard T. Baune, Chiara Fabbri, Antonina Luca, Dan Rujescu, Siegfried Kasper, Daniel Souery, Mariangela Tripodi, Alessandro Serretti, Maria Antonietta De Luca, A. Messina
article en
24 citations

Abstract

Our findings support the role of anhedonia as a modulating feature of MDD, being associated with a more severe depression profile. Moreover, anhedonic features are independent predictors of poor treatment response.

The International Journal of NeuropsychopharmacologyVol. 27(12)
Université Libre de Bruxelles (BE), Centre for Addiction and Mental Health (CA), Radboud University Nijmegen (NL), Vita-Salute San Raffaele University (IT), Tel Aviv University (IL), The University of Melbourne (AU), University of Münster (DE), Florey Institute of Neuroscience and Mental Health (AU), Università degli Studi di Enna Kore (IT), Sheba Medical Center (IL), Radboud University Medical Center (NL), Oasi Maria SS (IT), IRCCS Ospedale San Raffaele (IT), Istituti di Ricovero e Cura a Carattere Scientifico (IT), Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele (IT), Imperial College London (GB), Athens State University (US), Medical University of Vienna (AT), University of Bologna (IT)
European Commission, HORIZON EUROPE Framework Programme
No poverty
Openalex Percentile: Top 1%
Treatment of Major Depression
10.75
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