The role of CREB and MAPK signaling pathways in ATLL patients
The present study demonstrated that CREB gene expression was higher in the ATLL group than ACs, while there was no difference for MAPK. Therefore, this pathway may not strongly involve in the activation of CREB. The CREB may be a prognostic factor for the development of HTLV-I-associated diseases and can be used as a monitoring marker for the efficiency of the therapeutic regime and prognosis.
Authors
- Zahra Farjami
- Houshang Rafatpanah (ORCID: https://orcid.org/0000-0002-1061-5864)
- Mohammad Mehdi Akbarin (ORCID: https://orcid.org/0000-0002-1583-891X)
- Seyed Abdolrahim Rezaee (ORCID: https://orcid.org/0000-0001-6814-5992)
- Hossein Rahimi
Institutions
- Mashhad University of Medical Sciences (IR)
- Islamic Azad University, Mashhad (IR)
- Ghaem Hospital (IR)
Publication Details
- Journal
- AIDS Research and Therapy
- Published
- 2024-11-11
- DOI
- https://doi.org/10.1186/s12981-024-00664-x
- Citations
- 5
- Primary Topic
- Autoimmune and Inflammatory Disorders Research
- Type
- article
- Field-Weighted Citation Impact
- 2.27
Funders
- Mashhad University of Medical Sciences