miR-630 as a therapeutic target in pancreatic cancer stem cells: modulation of the PRKCI-Hedgehog signaling axis
MiR-630 emerges as a pivotal regulator in PCSC biology, opening up new avenues for targeted interventions in PC. The inhibitory effect of miR-630 on PCSC behavior underscores its potential as a valuable therapeutic target, offering insights into innovative treatment strategies for this challenging disease.
Authors
- Bangran Xu
- Chongwu He (ORCID: https://orcid.org/0009-0006-4510-944X)
- Lei Deng (ORCID: https://orcid.org/0000-0003-2647-4610)
- Daiwen Chen (ORCID: https://orcid.org/0000-0002-8351-7421)
- Jun Zou (ORCID: https://orcid.org/0009-0005-6863-1831)
- Sha Yang (ORCID: https://orcid.org/0000-0001-5264-261X)
Institutions
- Jiangxi University of Traditional Chinese Medicine (CN)
- Jiaxing University (CN)
- Jiangxi Provincial Cancer Hospital (CN)
Publication Details
- Journal
- Biology Direct
- Published
- 2024-11-11
- DOI
- https://doi.org/10.1186/s13062-024-00539-1
- Citations
- 4
- Primary Topic
- Hedgehog Signaling Pathway Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.94