Differences in Brain Volume in Military Service Members and Veterans After Blast-Related Mild TBI
In this cohort study of 774 veterans and active duty service members, robust volume differences associated with blast-related TBI were identified. Furthermore, these volume differences significantly mediated the association between blast-related mild TBI and cognitive function, indicating that this pattern of brain differences may have implications for daily functioning.
Authors
- Mary R. Newsome (ORCID: https://orcid.org/0000-0002-2112-0939)
- Sarah L. Martindale (ORCID: https://orcid.org/0000-0002-0059-3454)
- Jessica Gill (ORCID: https://orcid.org/0000-0002-3689-7441)
- Kimbra Kenney (ORCID: https://orcid.org/0000-0002-8138-7539)
- Sidney R. Hinds (ORCID: https://orcid.org/0000-0003-2231-6770)
- Brian Avants (ORCID: https://orcid.org/0000-0002-4212-3362)
- Emily L. Dennis (ORCID: https://orcid.org/0000-0001-7112-4009)
- Pashtun-Poh Shahim
- Elizabeth S Hovenden
- Carrie Esopenko (ORCID: https://orcid.org/0000-0001-8607-5633)
- David F. Tate (ORCID: https://orcid.org/0000-0003-0213-1920)
- Maya Troyanskaya (ORCID: https://orcid.org/0000-0002-4453-1466)
- Mary Jo Pugh (ORCID: https://orcid.org/0000-0003-4196-7763)
- Robert Shih (ORCID: https://orcid.org/0000-0001-8316-2061)
- Hannah M. Lindsey (ORCID: https://orcid.org/0000-0003-3826-854X)
- Jared A. Rowland (ORCID: https://orcid.org/0000-0002-3655-3411)
- Nicholas J. Tustison (ORCID: https://orcid.org/0000-0001-9418-5103)
- William C. Walker (ORCID: https://orcid.org/0000-0001-5813-3939)
- J. Kent Werner (ORCID: https://orcid.org/0000-0001-9858-2931)
- Elisabeth A. Wilde (ORCID: https://orcid.org/0000-0002-9839-4428)
- David X. Cifu (ORCID: https://orcid.org/0000-0003-1600-9387)
- Randall S. Scheibel
- James R. Stone
- Gerald E. York
Institutions
- National Institutes of Health (US)
- Michael E. DeBakey VA Medical Center (US)
- Uniformed Services University of the Health Sciences (US)
- Baylor College of Medicine (US)
- Virginia Commonwealth University (US)
- University of Utah (US)
- Ben Taub Hospital (US)
- Walter Reed National Military Medical Center (US)
- Anchorage Associates in Radiation Medicine (US)
- National Institute of Nursing Research (US)
- W. G. (Bill) Hefner VA Medical Center (US)
- Radiology Associates (US)
- Center for Neuroscience and Regenerative Medicine (US)
- National Institutes of Health Clinical Center (US)
- George E. Wahlen Department of VA Medical Center (US)
- Wake Forest University (US)
- University of Virginia (US)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- JAMA Network Open
- Published
- 2024-11-11
- DOI
- https://doi.org/10.1001/jamanetworkopen.2024.43416
- Citations
- 9
- Primary Topic
- Traumatic Brain Injury Research
- Type
- article
- Field-Weighted Citation Impact
- 3.48