Frailty Trajectories Preceding Dementia in the US and UK
These findings suggest that frailty measurements may be used to identify high-risk population groups for preferential enrolment into clinical trials for dementia prevention and treatment. Frailty itself may represent a useful upstream target for behavioral and societal approaches to dementia prevention.
Authors
- Marco Canevelli (ORCID: https://orcid.org/0000-0001-7333-6478)
- Jonny P Flint (ORCID: https://orcid.org/0000-0003-1738-9457)
- Emily H Gordon (ORCID: https://orcid.org/0000-0001-9985-6404)
- David Ward (ORCID: https://orcid.org/0000-0001-5476-9526)
- Thomas J. Littlejohns (ORCID: https://orcid.org/0000-0003-1177-6923)
- Ruth Eleanor Hubbard (ORCID: https://orcid.org/0000-0002-8688-5836)
- Janice M. Ranson (ORCID: https://orcid.org/0000-0001-9491-3940)
- David J. Llewellyn (ORCID: https://orcid.org/0000-0002-2441-4246)
- Isabelle F. Foote (ORCID: https://orcid.org/0000-0002-0253-4116)
- Erwin Stolz (ORCID: https://orcid.org/0000-0001-7393-1568)
- Lindsay Wallace (ORCID: https://orcid.org/0000-0002-3879-477X)
- Kenneth Rockwood
Institutions
- Dalhousie University (CA)
- Stockholm University (SE)
- The University of Queensland (AU)
- University of Colorado Boulder (US)
- Medical University of Graz (AT)
- QIMR Berghofer Medical Research Institute (AU)
- University of Exeter (GB)
- University of Cambridge (GB)
- Istituto Superiore di Sanità (IT)
- Princess Alexandra Hospital (AU)
- Nova Scotia Health Authority (CA)
- Karolinska Institutet (SE)
- University of Oxford (GB)
- Alzheimer Scotland (GB)
- National Centre for Disease Prevention and Control (IT)
- The Alan Turing Institute (GB)
- Sapienza University of Rome (IT)
- University of Edinburgh (GB)
Publication Details
- Journal
- JAMA Neurology
- Published
- 2024-11-11
- DOI
- https://doi.org/10.1001/jamaneurol.2024.3774
- Citations
- 35
- Primary Topic
- Frailty in Older Adults
- Type
- article
- Field-Weighted Citation Impact
- 12.05