DeepBP: Ensemble deep learning strategy for bioactive peptide prediction

In this study, CapsuleGAN, GRU, and CNN were successfully employed as base classifiers to implement ensemble learning, which not only achieved good results in the prediction of two datasets but also surpassed existing methods. The ability to predict peptides with strong ACE inhibitory activity and ACPs more accurately and quickly is significant, and this work provides valuable insights for predicting other functional peptides. The source code and dataset for this experiment are publicly available at https://github.com/Zhou-Jianren/bioactive-peptides .

Authors

Institutions

Publication Details

Journal
BMC Bioinformatics
Published
2024-11-11
DOI
https://doi.org/10.1186/s12859-024-05974-5
Citations
14
Primary Topic
Machine Learning in Bioinformatics
Type
article
Field-Weighted Citation Impact
3.27

Funders

Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

DeepBP: Ensemble deep learning strategy for bioactive peptide prediction

Fang Ge, Xiaohua Wang, Jianling Zhou, Xun Wang et al.
14 citations
BMC Bioinformatics
Machine Learning in Bioinformatics
3.27
article

DeepBP: Ensemble deep learning strategy for bioactive peptide prediction

Fang Ge, Xiaohua Wang, Jianling Zhou, Xun Wang, Ming Zhang
article en
14 citations

Abstract

In this study, CapsuleGAN, GRU, and CNN were successfully employed as base classifiers to implement ensemble learning, which not only achieved good results in the prediction of two datasets but also surpassed existing methods. The ability to predict peptides with strong ACE inhibitory activity and ACPs more accurately and quickly is significant, and this work provides valuable insights for predicting other functional peptides. The source code and dataset for this experiment are publicly available at https://github.com/Zhou-Jianren/bioactive-peptides .

BMC BioinformaticsVol. 25(1)
Nanjing University of Posts and Telecommunications (CN), Jiangsu University of Science and Technology (CN)
Nanjing University of Posts and Telecommunications, Nanjing University
Openalex Percentile: Top 7%
Machine Learning in Bioinformatics
3.27
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.