Probiotic-derived extracellular vesicles alleviate AFB1-induced intestinal injury by modulating the gut microbiota and AHR activation
LA.EVs alleviated AFB1-induced intestinal injury by modulating the gut microbiota, activating the intestinal AHR/IL-22 signalling, reducing the inflammatory response and promoting intestinal barrier repair in mice.
Authors
- Xingxiang Chen (ORCID: https://orcid.org/0000-0003-1625-4374)
- Jinyan Li (ORCID: https://orcid.org/0000-0003-1833-7413)
- Weili Kang (ORCID: https://orcid.org/0000-0002-0062-7351)
- Xianjiao Liu
- Shuiping Liu (ORCID: https://orcid.org/0000-0002-8831-7947)
- Kehe Huang (ORCID: https://orcid.org/0000-0003-4132-3052)
- Yubo Wang (ORCID: https://orcid.org/0000-0001-6977-239X)
- Jinyan Liu (ORCID: https://orcid.org/0009-0003-2254-7998)
- Yunhuan Liu (ORCID: https://orcid.org/0009-0007-3048-2521)
- Mengdie Shi
Institutions
- Nanjing Agricultural University (CN)
Publication Details
- Journal
- Journal of Nanobiotechnology
- Published
- 2024-11-11
- DOI
- https://doi.org/10.1186/s12951-024-02979-3
- Citations
- 21
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 4.91
Funders
- National Natural Science Foundation of China