Clinical outcomes of chimeric antigen receptor T-cell therapy following autologous hematopoietic stem cell transplantation in 38 patients with refractory/relapsed primary or secondary central nervous system lymphoma
CAR T-cell therapy following ASCT shows promising efficacy for r/r CNSL patients. Besides, SCNSL patients with CNS and systemic lesions have inferior treatment efficacy compared to those with CNS lesions only.
Authors
- Jiaying Wu (ORCID: https://orcid.org/0000-0002-7932-538X)
- Zhen Shang (ORCID: https://orcid.org/0000-0002-5471-7862)
- Yang Yang (ORCID: https://orcid.org/0000-0001-5157-9655)
- Fankai Meng (ORCID: https://orcid.org/0000-0002-6838-3955)
- Mi Zhou (ORCID: https://orcid.org/0000-0001-9923-5253)
- Yang Cao (ORCID: https://orcid.org/0000-0003-0152-639X)
- Wanying Liu (ORCID: https://orcid.org/0000-0001-9886-7013)
- Yi Xiao (ORCID: https://orcid.org/0000-0002-6234-3506)
- Xiaojian Zhu
- Yicheng Zhang
Institutions
- Tongji Hospital (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Cancer Immunology Immunotherapy
- Published
- 2024-11-11
- DOI
- https://doi.org/10.1007/s00262-024-03855-7
- Citations
- 5
- Primary Topic
- CAR-T cell therapy research
- Type
- article
- Field-Weighted Citation Impact
- 1.41
Funders
- National Natural Science Foundation of China