Assessment of genetically modified maize DP51291 (application GMFF‐2021‐0071)
Genetically modified maize DP51291 was developed to confer control against susceptible corn rootworm pests and tolerance to glufosinate-containing herbicide; these properties were achieved by introducing the <i>ipd072Aa, pmi</i> and <i>mo-pat</i> expression cassettes. The molecular characterisation data and bioinformatic analyses do not identify issues requiring food/feed safety assessment. None of the identified differences in the agronomic/phenotypic and compositional characteristics tested between maize DP51291 and its conventional counterpart needs further assessment, except for phosphorus in forage and manganese, proline, oleic acid (C18:1) and linoleic acid (C18:2) in grain, which do not raise safety and nutritional concerns. The GMO Panel does not identify safety concerns regarding the toxicity and allergenicity of the IPD072Aa, PAT and PMI proteins as expressed in maize DP51291 and finds no evidence that the genetic modification would change the overall allergenicity of maize DP51291. In the context of this application, the consumption of food and feed from maize DP51291 does not represent a nutritional concern in humans and animals. The GMO Panel concludes that maize DP51291 is as safe as its conventional counterpart and non-GM maize varieties tested, and no post-market monitoring of food/feed is considered necessary. In the case of accidental release of viable maize DP51291 grains into the environment, this would not raise environmental safety concerns. The post-market environmental monitoring plan and reporting intervals are in line with the intended uses of maize DP51291. The GMO Panel concludes that maize DP51291 is as safe as its conventional counterpart and the tested non-GM maize varieties with respect to potential effects on human and animal health and the environment.
Authors
- Paolo Lenzi
- José Ángel Gómez Ruiz (ORCID: https://orcid.org/0000-0001-9386-6185)
- Aleksandra Lewandowska (ORCID: https://orcid.org/0000-0002-1694-5151)
- Jean‐Luc Gallois (ORCID: https://orcid.org/0000-0003-0451-1740)
- Ruud A. de Maagd (ORCID: https://orcid.org/0000-0001-7049-2029)
- Francisco Barro (ORCID: https://orcid.org/0000-0002-7652-229X)
- Alan H. Schulman (ORCID: https://orcid.org/0000-0002-4126-6177)
- Antoine Messéan (ORCID: https://orcid.org/0000-0002-6634-6288)
- Silvia Federici (ORCID: https://orcid.org/0000-0001-7780-6430)
- Fabien Nogué (ORCID: https://orcid.org/0000-0003-0619-4638)
- Tilemachos Goumperis
- Frits Koning (ORCID: https://orcid.org/0000-0002-4007-5715)
- Josep Casacuberta (ORCID: https://orcid.org/0000-0002-5609-4152)
- Giuditta De Santis (ORCID: https://orcid.org/0000-0002-0280-4905)
- Dafni Maria Kagkli (ORCID: https://orcid.org/0000-0002-7351-135X)
- Pietro Piffanelli
- Eve Veromann (ORCID: https://orcid.org/0000-0002-0977-5270)
- Christoph C. Tebbe (ORCID: https://orcid.org/0000-0003-4861-0214)
- Ana M. Camargo (ORCID: https://orcid.org/0000-0002-5126-9371)
- Albert Braeuning (ORCID: https://orcid.org/0000-0003-3810-027X)
- Paschalina Grammatikou
- Kyriaki Xiftou
- F. Javier Moreno (ORCID: https://orcid.org/0000-0002-7637-9542)
- M. Epstein (ORCID: https://orcid.org/0000-0002-4755-0224)
- Giovanni Savoini
- Thomas Frenzel
- Franco Maria Neri
- Antonio Fernández Dumont
- Michele Ardizzone
- Tommaso Raffaello
- Andrea Gennaro
- Pilar Cubas
Institutions
- University of Essex (GB)
- European Food Safety Authority (IT)
- University of Helsinki (FI)
- Vrije Universiteit Brussel (BE)
- Consejo Superior de Investigaciones Científicas (ES)
- Estonian University of Life Sciences (EE)
- Leiden University Medical Center (NL)
- Federal Institute for Risk Assessment (DE)
- Istituto Giannina Gaslini (IT)
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement (FR)
- Institute for Biodiversity (DE)
- Département agronomie et sciences de l'environnement pour les agroécosystèmes (FR)
- Institut Jean-Pierre Bourgin (FR)
- Génétique et amélioration des fruits et légumes (FR)
- Instituto de Agricultura Sostenible (ES)
- Center for Research in Agricultural Genomics (ES)
- Saxon State Ministry for Science and the Arts (DE)
- Universidad Autónoma de Madrid (ES)
- University of Milano-Bicocca (IT)
- Universidad de Sevilla (ES)
- Wageningen University & Research (NL)
Publication Details
- Journal
- EFSA Journal
- Published
- 2024-11-01
- DOI
- https://doi.org/10.2903/j.efsa.2024.9059
- Citations
- 1
- Primary Topic
- Genetically Modified Organisms Research
- Type
- article
- Field-Weighted Citation Impact
- 0.60