Feedback regulation of <scp>VISTA</scp> and Treg by <scp>TNF</scp>‐α controls T cell responses in drug allergy

Our findings defining feedback regulation of VISTA and Treg cells by TNF-α in different stages of the drug-specific T-cell response and, indicate that a Treg agonists, instead of TNF-α antagonists, could be used for treatment of patients with progressive SCARs.

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Publication Details

Journal
Allergy
Published
2024-11-11
DOI
https://doi.org/10.1111/all.16393
Citations
6
Primary Topic
Drug-Induced Adverse Reactions
Type
article
Field-Weighted Citation Impact
2.69
Controls
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article

Feedback regulation of VISTA and Treg by TNF‐α controls T cell responses in drug allergy

Yonghu Sun, Xiaoli Meng, Monday O. Ogese, Dean John Naisbitt et al.
6 citations
Allergy
Drug-Induced Adverse Reactions
2.69
article

Feedback regulation of VISTA and Treg by TNF‐α controls T cell responses in drug allergy

Yonghu Sun, Xiaoli Meng, Monday O. Ogese, Dean John Naisbitt, Joshua Gardner, Xiaotong Xue, Zhenzhen Wang, Zihao Mi, Furen Zhang, Suiting Ao, Hong Liu, Qing Zhao, Lele Sun, Jiabao You, Tingting Liu
article en
6 citations

Abstract

Our findings defining feedback regulation of VISTA and Treg cells by TNF-α in different stages of the drug-specific T-cell response and, indicate that a Treg agonists, instead of TNF-α antagonists, could be used for treatment of patients with progressive SCARs.

AllergyVol. 80(5)
Shandong University of Traditional Chinese Medicine (CN), University of Liverpool (GB), Shandong Provincial Institute of Dermatology and Venereology (CN), Shandong First Medical University (CN)
Good health and well-being
Openalex Percentile: Top 10%
Drug-Induced Adverse Reactions
2.69
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Feedback regulation of <scp>VISTA</scp> and Treg by <scp>TNF</scp>‐α controls T cell responses in drug allergy — Yonghu Sun, Xiaoli Meng, et al. · Allergy (2024) | TGRS Research Map | TGRS