Deciphering influence of donor age on adipose-derived stem cells: in vitro paracrine function and angiogenic potential
Our results show cells from young and old donors exhibit no difference in all assessed parameters, suggesting all patients could be included in clinical applications. We emphasized the leading role of ASC in angiogenesis, without impairment with age, where secretome is a key but not sufficient actor.
Authors
- Céline Auxenfans (ORCID: https://orcid.org/0000-0001-8599-8479)
- Chloe Trotzier (ORCID: https://orcid.org/0009-0003-4059-0615)
- Philippe Delannoy
- Hakima Abdessadeq
- Clement Bellanger
- Ali Mojallal
Institutions
- Université Claude Bernard Lyon 1 (FR)
- L'Oréal (France) (FR)
- Hospices Civils de Lyon (FR)
Publication Details
- Journal
- Scientific Reports
- Published
- 2024-11-11
- DOI
- https://doi.org/10.1038/s41598-024-73875-x
- Citations
- 6
- Primary Topic
- Mesenchymal stem cell research
- Type
- article
- Field-Weighted Citation Impact
- 2.63
Funders
- L'Oreal USA