A CASE SERIES ON LUNG ADENOCARCINOMA WITH VARYING CLINICAL PRESENTATION

Lung cancer is the most common cause of death among all cancer deaths. Adenocarcinoma of the lung is commonly seen in females and nonsmokers. It is a subtype of non-small cell lung cancer (NSCLC). The lesions are more peripherally located and tend to be smaller. Histologically, adenocarcinoma is present as atypical adenomatous hyperplasia (precursor lesion) which progresses to adenocarcinoma in situ and later develops into invasive adenocarcinoma. Adenocarcinoma of the lung is diagnosed by histopathological confirmation via thoracocentesis of pleural effusion, excisional biopsy of an accessible lymph node, bronchoscopy guided lung biopsy, transthoracic needle aspiration, sputum cytology, CT-guided biopsy, medical as well as video-assisted thoracoscopy. This case series comprises three patients with primary lung adenocarcinoma who had been presented with atypical clinical features and emphasised challenges faced in diagnosis.