Senolysis potentiates endothelial progenitor cell adhesion to and integration into the brain vasculature
Combining progenitor cell therapy with senolytic therapy and the prior activation of EPCs are promising for improving EPC adhesion to and integration into the cerebral vasculature and could help rejuvenate the ageing brain.
Authors
- Tania Lam (ORCID: https://orcid.org/0000-0002-5782-2537)
- Attila E. Farkas (ORCID: https://orcid.org/0000-0002-9519-5968)
- Imola Wilhelm (ORCID: https://orcid.org/0000-0003-2366-7337)
- Anca Hermenean (ORCID: https://orcid.org/0000-0001-8510-6653)
- Claudine Kiéda (ORCID: https://orcid.org/0000-0002-7573-029X)
- István A. Krizbai (ORCID: https://orcid.org/0000-0002-0764-1527)
- Balázs István Tóth (ORCID: https://orcid.org/0000-0002-4103-4333)
Institutions
- Centre National de la Recherche Scientifique (FR)
- University of Szeged (HU)
- HUN-REN Szegedi Biológiai Kutatóközpont (HU)
- Vasile Goldis Western University of Arad (RO)
- Centre de Biophysique Moléculaire (FR)
- Institute of Biophysics (HU)
- Narodowy Instytut Leków (PL)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2024-11-11
- DOI
- https://doi.org/10.1186/s13287-024-04042-2
- Citations
- 2
- Primary Topic
- Angiogenesis and VEGF in Cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.47
Funders
- Magyar Tudományos Akadémia
- Nemzeti Kutatási Fejlesztési és Innovációs Hivatal
- National Research, Development and Innovation Office