Functional expression of recombinant insulins in Saccharomyces cerevisiae
Therefore, replacement of the C-peptide of insulin with the HL18 fusion partner and use of Kex2p for in vitro processing of proinsulin guarantees the economic production of animal insulins in yeast.
Authors
- Bong Hyun Sung (ORCID: https://orcid.org/0000-0002-8992-1118)
- Jung‐Hoon Sohn (ORCID: https://orcid.org/0000-0002-5311-6424)
- Jung‐Hoon Bae (ORCID: https://orcid.org/0000-0002-9224-367X)
- Hyun‐Jin Kim (ORCID: https://orcid.org/0000-0002-7284-3547)
- Mi Jin Kim (ORCID: https://orcid.org/0000-0002-4505-4083)
- Se-Lin Park
Institutions
- Cell Biotech (South Korea) (KR)
- Korea Research Institute of Bioscience and Biotechnology (KR)
Publication Details
- Journal
- Microbial Cell Factories
- Published
- 2024-11-11
- DOI
- https://doi.org/10.1186/s12934-024-02571-2
- Citations
- 2
- Primary Topic
- Microbial Metabolic Engineering and Bioproduction
- Type
- article
- Field-Weighted Citation Impact
- 0.47
Funders
- National Research Foundation
- Ministry of Agriculture, Food and Rural Affairs
- Rural Development Administration
- Korea Research Institute of Bioscience and Biotechnology
- Ministry of Science and ICT, South Korea