Exploring lncRNA expression in follicular fluid exosomes of patients with obesity and polycystic ovary syndrome based on high-throughput sequencing technology
A preliminary differential expression profile of lncRNAs in exosomes of patients with obesity and PCOS was established by transcriptomic analysis of these individuals. Our bioinformatics analysis results may be applicable to further study of the impact mechanism involving obesity and PCOS. These differentially expressed lncRNAs maybe served as potential biomarkers for in-depth studies of the occurrence, development on Follicle quality and function for patients with PCOS in the future.
Authors
- Liwei Dong (ORCID: https://orcid.org/0000-0003-2116-1674)
- Fang Lian (ORCID: https://orcid.org/0000-0002-5590-7262)
- Xin Xin (ORCID: https://orcid.org/0000-0003-3987-0479)
- Jiaxi Li (ORCID: https://orcid.org/0000-0002-2007-6366)
- Wen‐Cheng Chen (ORCID: https://orcid.org/0000-0002-5581-9991)
- Yue Qiu (ORCID: https://orcid.org/0000-0003-3546-4510)
- Haicui Wu (ORCID: https://orcid.org/0000-0003-3313-3697)
Institutions
- Shandong University of Traditional Chinese Medicine (CN)
- Affiliated Hospital of Shandong University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Journal of Ovarian Research
- Published
- 2024-11-11
- DOI
- https://doi.org/10.1186/s13048-024-01552-8
- Citations
- 4
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 1.14
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Shandong Province