GelMA hydrogels reinforced by PCL@GelMA nanofibers and bioactive glass induce bone regeneration in critical size cranial defects
We successfully prepared a novel injectable composite hydrogel, and the design of the composite hydrogels shows significant potential for enhancing biocompatibility, angiogenesis, and improving osteogenic and angiogenic marker expression, and has a beneficial effect on producing an optimal microenvironment that promotes bone repair.
Authors
- Tong S. Wu (ORCID: https://orcid.org/0000-0001-8822-1868)
- Chenghao Yu (ORCID: https://orcid.org/0000-0002-2542-944X)
- Zhuoli Zhang (ORCID: https://orcid.org/0000-0001-7219-9141)
- Jinli Chen (ORCID: https://orcid.org/0000-0002-4071-4388)
- Tengbo Yu (ORCID: https://orcid.org/0000-0002-4270-7317)
- Yawen Wang (ORCID: https://orcid.org/0000-0003-3749-1416)
- Yuanfei Wang (ORCID: https://orcid.org/0000-0002-5561-7038)
- Xiaopei Zhang
- Tianrui Wang (ORCID: https://orcid.org/0000-0001-9911-4806)
Institutions
- Qingdao University (CN)
- University of California, Irvine (US)
- Affiliated Hospital of Qingdao University (CN)
- Qingdao Municipal Hospital (CN)
Publication Details
- Journal
- Journal of Nanobiotechnology
- Published
- 2024-11-11
- DOI
- https://doi.org/10.1186/s12951-024-02980-w
- Citations
- 29
- Primary Topic
- Bone Tissue Engineering Materials
- Type
- article
- Field-Weighted Citation Impact
- 5.35
Funders
- Qingdao Key Health Discipline Development Fund
- National Natural Science Foundation of China
- Natural Science Foundation of Shandong Province
- Key Technology Research and Development Program of Shandong