STUDY OF USEFULNESS OF SOFA SCORE IN PATIENTS WITH MULTIPLE ORGAN DYSFUNCTION IN ICU

Background: Multiple Organ Dysfunction Syndrome (MODS) is a common cause of Intensive Care Unit (ICU) mortality and morbidity. The aim of the study was to determine morbidity and mortality of patients with multiple organ dysfunction in ICU &to prognostic the patients by using SOFA Score. Methodology: The study was done on 50 adult patients admitted to the medical & surgical ICU. The detailed history, clinical examination and laboratory investigations were done. Various profiles between two groups; survivor group and non-survivor, were done by the use of SOFA Score. The SOFA score of 6 variables, each representing an organ System. The worst physiological variables were collected serially every 24 hours of patients ICU admission. The worst measurement was defined as the measure that correlates to the highest number of points. Results:In our study, 36 patients died and 14 patients survived. The extensive study of SOFA score was done from day 1 to the last day. The SOFA score on day 1 was high among non-survivors than survivors but the SOFA score on day 3 was better compared with SOFA score on day 1 as the tool for outcome prediction. SOFA score was significantly low especially on day 3 (6.84±2.96) in survivor group as compared to non-survivor group whose mean day 3 value being (13.42±4.060). Total SOFA Score and Mean SOFA Score were effective in predicting the outcome patients with Sensitivity of 77.8% and 97.2% respectively and Specificity of 78.6% and 100% respectively. Conclusion: SOFA score has been validated extensively for prognostication so serial measurement of SOFA score during first week is a very useful tool in predicting the outcome.