IMPACT OF CHRONIC RENAL FUNCTION DURING THE TREATMENT OF TUBERCULOSIS

Introduction- CHRONIC RENAL FAILURE (CRF) is an established risk factor for tuberculosis (TB). Both TB incidence and prevalence are known to be higher in patients with CRF than in the general population. CRF is becoming increasingly common. The incidence and prevalence of patients on haemodialysis are respectively 4.9 and 13 per 100,000 population, and 35,000 CRF patients are estimated to currently live in Agra region. Despite the relatively high population level burden of CRF and increased risk of TB among patients with CRF, there are limited data on outcomes of CRF patients treated for TB. The majority of data to date are from case series, some of which have reported high and others low rates of adverse events and mortality. Few studies have directly compared outcomes in TB patients with and without CRF. Impact of Chronic renal function during the treatment of tuberculosis Aim- Material and Method Patients. - A case-control study of 50 diagnosed TB patients conducted at Biochemistry department in collaboration with TB and Chest Department at Sarojini Naidu Medical College , AGRA. In this study Blood Urea and Uric acid were found mild signi Result- ficant [<0.05] in case 83.1±34.2 (Mean±SD) as comparison of healthy person (Mean±SD) 80.3±30.7. Serum Creatinine were found significant [<0.001] in case 31.6±30.0 (Mean±SD) as comparisons of healthy person (Mean±SD) 18.5±16.09. TB patients with CRF are at increas Conclusion- ed risk of death. More intensive monitoring of patients with CRF should be considered by the National TB Programme.