Dose Optimization of Fluconazole After Initial Treatment Failure in Pulmonary Cryptococcosis in an Obese Patient with Type 2 Diabetes and Cirrhosis: A Case Report
This case suggests that fluconazole antifungal therapy for pulmonary cryptococcal infection should fully consider the risk of comorbidities in patients. If necessary, medication dosage can be adjusted according to weight, and it is recommended to use lean bodyweight for evaluation and optimization. In addition, close attention should be paid to liver and kidney function.
Authors
- Shuyun Xu (ORCID: https://orcid.org/0000-0002-2647-754X)
- Zhen Wang (ORCID: https://orcid.org/0000-0002-8174-8496)
- Jin Shang (ORCID: https://orcid.org/0000-0002-9122-3298)
- Yang Yang (ORCID: https://orcid.org/0000-0001-9942-058X)
Institutions
- Tongji Hospital (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Infection and Drug Resistance
- Published
- 2024-11-01
- DOI
- https://doi.org/10.2147/idr.s491615
- Citations
- 1
- Primary Topic
- Fungal Infections and Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.39
Funders
- Health Commission of Hubei Province