Electroacupuncture alleviates neuropathic pain in a rat model of CCD via suppressing P2X3 expression in dorsal root ganglia
Our findings suggest that 2/100 Hz EA alleviates neuropathic pain in rats by inhibiting the upregulation of P2X3 receptors in the ipsilateral DRG. This study backs up EA as a viable treatment option for sciatica and low back pain in clinical settings.
Authors
- Yongliang Jiang (ORCID: https://orcid.org/0000-0002-9937-7398)
- Xiaomei Shao (ORCID: https://orcid.org/0000-0002-1637-1178)
- Yinmu Zheng
- Yurong Kang
- Xiaofen He (ORCID: https://orcid.org/0000-0003-4212-5584)
- Siyi Li (ORCID: https://orcid.org/0000-0003-1470-7421)
- Yu Zheng (ORCID: https://orcid.org/0009-0002-9169-6105)
- Jianqiao Fang (ORCID: https://orcid.org/0000-0003-4499-0352)
- Minjian Jiang
- Zhouyuan Wei
- Hengyu Chi
Institutions
- Zhejiang Chinese Medical University (CN)
- The Third Affiliated Hospital of Zhejiang Chinese Medical University (CN)
Publication Details
- Journal
- Chinese Medicine
- Published
- 2024-11-11
- DOI
- https://doi.org/10.1186/s13020-024-01030-9
- Citations
- 3
- Primary Topic
- Pain Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.98
Funders
- State Administration of Traditional Chinese Medicine of the People's Republic of China
- Zhejiang Traditional Chinese Medicine Administration
- Natural Science Foundation of Zhejiang Province