Genetic predisposition to vaccine‐induced immune thrombotic thrombocytopenia
Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a rare prothrombotic disorder with a unique clonality-restricted immunological profile. The study by Petito and Bury et al. provides insight into the role of HLA polymorphisms and an inherent predisposition to VITT. Commentary on: Petito et al. Association of human leucocyte antigen loci with vaccine-induced immune thrombotic thrombocytopenia: Potential role of the interaction between platelet factor 4-derived peptides and MHC-II. Br J Haematol 2025; 206:290-295.
Authors
- Donald M. Arnold
- Guillaume Paré (ORCID: https://orcid.org/0000-0002-6795-4760)
- Ishac Nazy (ORCID: https://orcid.org/0000-0002-5695-4343)
Institutions
- McMaster University (CA)
Publication Details
- Journal
- British Journal of Haematology
- Published
- 2024-11-10
- DOI
- https://doi.org/10.1111/bjh.19885
- Citations
- 6
- Primary Topic
- Heparin-Induced Thrombocytopenia and Thrombosis
- Type
- article
- Field-Weighted Citation Impact
- 3.44