Establishing a dominant early larval sex-selection strain in the Asian malaria vector Anopheles stephensi
SEPARATOR's independence from sex-chromosome linkage provides resistance to breakage that could be mediated by meiotic recombination and chromosomal rearrangements, making it highly suitable for mass male releases. By enabling precise male selection from the first instar larval stages, SEPARATOR represents a significant advancement that will aid in the genetic biocontrol for Anopheles mosquitoes.
Authors
- Sammy Lee
- Omar S. Akbari (ORCID: https://orcid.org/0000-0002-6853-9884)
- Shih‐Che Weng (ORCID: https://orcid.org/0000-0003-3315-9125)
- Fangying Chen (ORCID: https://orcid.org/0000-0003-0840-5726)
- Ming Li (ORCID: https://orcid.org/0000-0002-7578-4968)
- Dylan Can Turksoy
- Connor Gerry
Institutions
- University of California San Diego (US)
Publication Details
- Journal
- Infectious Diseases of Poverty
- Published
- 2024-11-11
- DOI
- https://doi.org/10.1186/s40249-024-01256-7
- Citations
- 12
- Primary Topic
- Malaria Research and Control
- Type
- article
- Field-Weighted Citation Impact
- 6.52
Funders
- National Institutes of Health