Altered carnitine transporter genes (SLC22A5, SLC22A16, SLC6A14) expression pattern among lung cancer patients
The expression levels of genes encoding carnitine transporters are diverse, hinting at a potentially altered carnitine metabolism in LC patients. Notably, this variance is not uniform and exhibits specificity across LC subtypes, with marked distinctions between LUAD and LUSC. The correlation between gene expression levels and OS of patients underlines the prognostic significance of <i>SLC</i> genes within these cancer subtypes.
Authors
- Szymon Wcisło (ORCID: https://orcid.org/0000-0001-6984-9924)
- Dagmara Szmajda‐Krygier (ORCID: https://orcid.org/0000-0002-9524-6032)
- Sławomir Jabłoński (ORCID: https://orcid.org/0000-0002-6059-8791)
- Ewa Balcerczak
- Adrian Krygier (ORCID: https://orcid.org/0000-0003-1525-1577)
- Konrad Kędzia (ORCID: https://orcid.org/0000-0002-7453-9397)
Institutions
- Medical University of Lodz (PL)
Publication Details
- Journal
- Translational Lung Cancer Research
- Published
- 2024-11-01
- DOI
- https://doi.org/10.21037/tlcr-24-448
- Citations
- 5
- Primary Topic
- Metabolism and Genetic Disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.91
Funders
- Uniwersytet Łódzki