Pathogenesis and Biomarkers of Cancer-Related Ischemic Stroke
In the present study, the increased NLR, PLR, ICAM-1 and D-dimer were expected to be biomarkers of CRIS, indicating that hypercoagulability mediated by cancer inflammation and endothelial damage may be the pathogenesis of CRIS. The novel findings in the present study will facilitate clinicians to identify the patients at high risk of CRIS. Because of the small sample size, the findings need to be validated by prospective large-sample studies in the future.
Authors
- Gengyu Cen (ORCID: https://orcid.org/0000-0003-3609-6633)
- Xue Wang (ORCID: https://orcid.org/0000-0001-8736-930X)
- Yiting Song (ORCID: https://orcid.org/0000-0003-3861-7826)
- Shijian Chen (ORCID: https://orcid.org/0000-0001-6547-3608)
- Zhijian Liang (ORCID: https://orcid.org/0009-0001-4339-5095)
- Jun Wang (ORCID: https://orcid.org/0000-0001-8411-9196)
- Qiuhui Huang (ORCID: https://orcid.org/0000-0001-8782-2709)
- Jing Li (ORCID: https://orcid.org/0009-0005-1479-8548)
Institutions
- Guangxi Medical University (CN)
- First Affiliated Hospital of GuangXi Medical University (CN)
- Tumor Hospital of Guangxi Medical University (CN)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2024-11-01
- DOI
- https://doi.org/10.2147/jir.s493406
- Citations
- 2
- Primary Topic
- Acute Ischemic Stroke Management
- Type
- article
- Field-Weighted Citation Impact
- 0.77
Funders
- National Natural Science Foundation of China