Evaluating the Diagnostic and Prognostic Value of Interleukin-6 (IL-6) and Soluble Triggering Receptor Expressed on Myeloid Cells-1 (sTREM-1) in Systemic Inflammatory Response Syndrome (SIRS) and Sepsis in Adults
Our findings highlight the potential of sTREM-1, IL-6, and lactate as early diagnostic and prognostic markers in sepsis, where sTREM-1 is a critical biomarker for identifying high-risk patients. Further studies with larger cohorts are required to validate these results and explore the sTREM-1 clinical utility in guiding therapeutic interventions in sepsis management.
Authors
- Nino Gvajaia
- G Ormotsadze (ORCID: https://orcid.org/0000-0002-0283-0281)
- E Khuchua
- Tamar V Sanikidze (ORCID: https://orcid.org/0000-0003-1618-5276)
- Tamar Didbaridze (ORCID: https://orcid.org/0000-0001-7485-4330)
- Elene Pachkoria (ORCID: https://orcid.org/0000-0002-6273-9455)
- Vasil Kupradze
- L Ratiani (ORCID: https://orcid.org/0000-0002-2122-8915)
Institutions
- Tbilisi State University (GE)
- Tbilisi State Medical University (GE)
Publication Details
- Journal
- Cureus
- Published
- 2024-11-08
- DOI
- https://doi.org/10.7759/cureus.73310
- Citations
- 2
- Primary Topic
- Inflammation biomarkers and pathways
- Type
- article
- Field-Weighted Citation Impact
- 0.48