Cell Communications Between GCs and Macrophages Contribute to the Residence of Macrophage in Preovulatory Follicles
After luteinizing hormone (LH)/HCG surge, progesterone promotes the expression of FN1 in GCs by acting on the receptor PGR, and then GCs enhance the adhesion of macrophages by FN1-ITGB1 interaction, further leading to the result that macrophages perform diverse functional activities to maintain tissue homeostasis during ovulation.
Authors
- Ce Zhang (ORCID: https://orcid.org/0000-0001-7350-4187)
- Huihua Wu (ORCID: https://orcid.org/0000-0002-0337-4353)
- Nannan Zhao
- Ming‐Qing Li (ORCID: https://orcid.org/0000-0002-9276-0722)
- Hong Li (ORCID: https://orcid.org/0000-0002-6186-2152)
- Rui Zhu (ORCID: https://orcid.org/0000-0001-9389-9948)
- Qingxia Meng (ORCID: https://orcid.org/0009-0005-0666-7425)
- Fuxin Wang (ORCID: https://orcid.org/0000-0001-7467-8074)
- Liang Gao (ORCID: https://orcid.org/0000-0002-5322-7343)
Institutions
- Shanghai Jiao Tong University (CN)
- International Peace Maternity & Child Health Hospital (CN)
- Suzhou Municipal Hospital (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- American Journal of Reproductive Immunology
- Published
- 2024-11-01
- DOI
- https://doi.org/10.1111/aji.70009
- Primary Topic
- Reproductive System and Pregnancy
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Science Foundation
- National Natural Science Foundation of China
- Nanjing Medical University