Sonochemical Synthesis of Silver Nanoparticles and its Nanomedicinal Activities Against Staphylococcus aureus

The global rise of antibiotic-resistant bacteria due to the overuse of commercial antibiotics poses a significant public health threat. As a result, researchers have been exploring new antibacterial agents and approaches, including the field of nanomedicine. This study aims to produce silver nanoparticles (AgNPs) using lactose as a reducing agent through an ultrasound-assisted procedure and evaluate their anti-staphylococcal properties. AgNPs were synthesized using a one-pot ultrasound-assisted method with silver nitrate as the precursor and lactose as the reducing agent while the antibacterial activity was tested against Staphylococcus aureus using the agar well diffusion method. The synthesized AgNPs exhibited strong antibacterial activity, demonstrating potential as nanomedicine. These findings suggest that AgNPs could be valuable in combating antibiotic resistance and functional in the healthcare industry as an alternative antibacterial agent.