Studies on Metal Complexes of Pyrazole Bearing Ligand with Their Antimicrobial Screening

In present research article, we reported the synthesise of novel hetertocyclic ligand namely,5-((3-((1H-benzimidazol-1-yl)methyl)-5-phenyl-1H-pyrazol-1-yl) methyl)-8-hydroxy quinoline (BIPPHQ) from 5-chloro methyl-8-hydroxy quinoline and 1-((5-phenyl-1H-pyrazol-3-yl) methyl)-1H-benzimidazole (BIPP). The BIPP was synthsised by the reaction between hydrazine hydrate with 1-(1H-benzimidazol-1-yl)-4-phenylbut-3-en-2-one (BIPB), which was synthesisd from 1-(1H-benzimidazol-1-yl)propan-2-one (BIP) and benzaldehyde. The transition metal complxes of 5-((3-((1H-benzimidazol-1-yl)methyl)-5-phenyl-1H-pyrazol-1-yl)methyl)-8-hydroxy quinoline (BIPPHQ) were sythsised and analysed with the help of elemen conten analysis, spectroscopic data analysis, ratio of metal and ligand and also magneic parameters. The BIPPHQ and etal coplexes also screened for antimicrobial study.

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Publication Details

Journal
Oriental Journal Of Chemistry
Published
2024-10-31
DOI
https://doi.org/10.13005/ojc/400522
Primary Topic
Synthesis and biological activity
Type
article
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article

Studies on Metal Complexes of Pyrazole Bearing Ligand with Their Antimicrobial Screening

Rakesh Patel, Vikram Panchal
Oriental Journal Of Chemistry
Synthesis and biological activity
article

Studies on Metal Complexes of Pyrazole Bearing Ligand with Their Antimicrobial Screening

Rakesh Patel, Vikram Panchal
article en

Abstract

In present research article, we reported the synthesise of novel hetertocyclic ligand namely,5-((3-((1H-benzimidazol-1-yl)methyl)-5-phenyl-1H-pyrazol-1-yl) methyl)-8-hydroxy quinoline (BIPPHQ) from 5-chloro methyl-8-hydroxy quinoline and 1-((5-phenyl-1H-pyrazol-3-yl) methyl)-1H-benzimidazole (BIPP). The BIPP was synthsised by the reaction between hydrazine hydrate with 1-(1H-benzimidazol-1-yl)-4-phenylbut-3-en-2-one (BIPB), which was synthesisd from 1-(1H-benzimidazol-1-yl)propan-2-one (BIP) and benzaldehyde. The transition metal complxes of 5-((3-((1H-benzimidazol-1-yl)methyl)-5-phenyl-1H-pyrazol-1-yl)methyl)-8-hydroxy quinoline (BIPPHQ) were sythsised and analysed with the help of elemen conten analysis, spectroscopic data analysis, ratio of metal and ligand and also magneic parameters. The BIPPHQ and etal coplexes also screened for antimicrobial study.

Oriental Journal Of ChemistryVol. 40(5)
Clean water and sanitation
Openalex Percentile: Top 85%
Synthesis and biological activity
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