Enhanced in vivo Stability and Antitumor Efficacy of PEGylated Liposomes of Paclitaxel Palmitate Prodrug
This prodrug technology combined with liposomes is a simple and effective therapeutic strategy with promising developmental prospects in tumor-targeted therapy owing to its ability to convert PTX into a long-circulating nano drug with low toxicity, high pharmacodynamics, and good stability in vivo.
Authors
- Haisheng He (ORCID: https://orcid.org/0000-0002-5205-7426)
- Zongguang Tai (ORCID: https://orcid.org/0000-0001-5603-745X)
- Yi Lü (ORCID: https://orcid.org/0000-0002-9655-7510)
- Haiyan Zhang (ORCID: https://orcid.org/0000-0002-2877-2040)
- Hang Chen (ORCID: https://orcid.org/0000-0002-6699-3047)
- Jianming Chen (ORCID: https://orcid.org/0000-0001-8773-8494)
- Wei Wu (ORCID: https://orcid.org/0000-0002-0164-0814)
- Xinyu Wang (ORCID: https://orcid.org/0000-0002-5249-0326)
- Xin Wu (ORCID: https://orcid.org/0000-0002-3839-4768)
Institutions
- Tongji University (CN)
- Fudan University (CN)
- Shanghai Skin Disease Hospital (CN)
Publication Details
- Journal
- International Journal of Nanomedicine
- Published
- 2024-11-01
- DOI
- https://doi.org/10.2147/ijn.s488369
- Citations
- 10
- Primary Topic
- Nanoparticle-Based Drug Delivery
- Type
- article
- Field-Weighted Citation Impact
- 1.73