Genetic profiling of metastatic colon adenocarcinoma in Iranian patients: Insights into pathogenic variants and tumor characteristics
The study highlights the genetic diversity in Persian patients with metastatic colon adenocarcinoma and demonstrated that APC and TP53 variants were the most prevalent, while KRAS and ERBB2 variants were associated with specific tumor sites. These findings provide a basis for personalized treatment strategies in CRC among Persian population.
Authors
- Reza Jafarzadeh Esfehani (ORCID: https://orcid.org/0000-0002-9177-994X)
- Ali Kermani (ORCID: https://orcid.org/0000-0001-9298-7970)
- Parnian Boroonsara
- Naeeme Shakour
Institutions
- Mashhad University of Medical Sciences (IR)
- Academic Center for Education, Culture and Research (IR)
Publication Details
- Journal
- Cancer Genetics
- Published
- 2024-11-01
- DOI
- https://doi.org/10.1016/j.cancergen.2024.11.003
- Primary Topic
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00