Clinicopathological Analysis of a European Cohort of <i>MYOD1</i> Mutant Rhabdomyosarcomas in Children and Young Adults
This MYOD1 mutant cohort demonstrates increased MYOD and reduced MYF4 immunostaining, high risk of local failure and poor survival in agreement with other studies. Increased treatment intensity and improved local control should be considered for these patients.
Authors
- JANET M. SHIPLEY (ORCID: https://orcid.org/0000-0001-6748-8678)
- Svetlana Tafjord
- Paula Proszek (ORCID: https://orcid.org/0000-0002-0780-6790)
- Rita Alaggio (ORCID: https://orcid.org/0000-0003-3915-3816)
- Maja Česen (ORCID: https://orcid.org/0000-0003-2434-8960)
- Julia Chisholm (ORCID: https://orcid.org/0000-0003-3479-7997)
- С. В. Попов (ORCID: https://orcid.org/0000-0002-0567-4616)
- Joanna Selfe (ORCID: https://orcid.org/0000-0002-9556-3628)
- Madeleine Adams (ORCID: https://orcid.org/0000-0002-5277-5487)
- Anna Kelsey (ORCID: https://orcid.org/0000-0003-3638-1266)
- Meriel Jenney (ORCID: https://orcid.org/0000-0002-2612-4621)
- Giuseppe Maria Milano (ORCID: https://orcid.org/0000-0002-0250-6043)
- Lucia Tombolan (ORCID: https://orcid.org/0000-0002-8208-6244)
- Antonina Parafioriti (ORCID: https://orcid.org/0000-0002-4091-1541)
- Angelica Zin (ORCID: https://orcid.org/0000-0002-7104-273X)
- Daniela Di Carlo (ORCID: https://orcid.org/0000-0003-0573-8576)
- Edmund Cheesman (ORCID: https://orcid.org/0000-0003-4742-388X)
- Hélene Schlecht (ORCID: https://orcid.org/0000-0002-1916-6575)
Institutions
- Oslo University Hospital (NO)
- Qatar Airways (Qatar) (QA)
- Royal Marsden NHS Foundation Trust (GB)
- University of Padua (IT)
- Institute of Cancer Research (GB)
- Ljubljana University Medical Centre (SI)
- St Mary's Hospital (GB)
- St Mary's Hospital (GB)
- Istituto Ortopedico Gaetano Pini (IT)
- Noah's Ark Children's Hospital for Wales (GB)
- Royal Marsden Hospital (GB)
- Bambino Gesù Children's Hospital (IT)
- Royal Manchester Children's Hospital (GB)
- Città della Speranza Foundation (IT)
Publication Details
- Journal
- Pediatric Blood & Cancer
- Published
- 2024-11-07
- DOI
- https://doi.org/10.1002/pbc.31428
- Citations
- 6
- Primary Topic
- Sarcoma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.51
Funders
- Royal Marsden NHS Foundation Trust
- Royal Marsden Cancer Charity
- National Institute for Health and Care Research
- Department of Health and Social Care
- Birmingham Biomedical Research Centre