Genetically predicted serum ferritin mediates the association between inflammatory cytokines and non-alcoholic fatty liver disease
In conclusion, our study identified a causal relationship between inflammatory cytokines and NAFLD, with a small proportion of the effect mediated by ferritin, but a majority of the effect of inflammatory cytokines on NAFLD remains unclear. Further research is needed on additional risk factors as potential mediators.
Authors
- Linpu Ge (ORCID: https://orcid.org/0009-0000-5818-7427)
- XiaoQian Liu
- Jian-Hong Jin
- BaoFa Wang
Institutions
- Zhejiang Chinese Medical University (CN)
- The Third Affiliated Hospital of Zhejiang Chinese Medical University (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2024-11-08
- DOI
- https://doi.org/10.3389/fendo.2024.1437999
- Citations
- 1
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.39
Funders
- Medical Scientific Research Foundation of Zhejiang Province, China
- Department of Health of Zhejiang Province